Press reviews
#COVID19 #SARSCoV2 #vaccine
COVID-19, caused by SARS-CoV-2, remains a major global health threat. While first-generation mRNA and adenoviral vector vaccines have significantly reduced mortality and the severity of acute forms, several limitations remain. Their effectiveness tends to decline against emerging variants, notably due to mutations in the spike protein, which is the prima...
COVID-19, caused by SARS-CoV-2, remains a major global health threat. While first-generation mRNA and adenoviral vector vaccines have significantly reduced mortality and the severity of acute forms, several limitations remain. Their effectiveness tends to decline against emerging variants, notably due to mutations in the spike protein, which is the prima...
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#Dengue #Vaccine #Immunity #ADE #Virus
#Immunogenicity
Dengue is a major arboviral disease affecting millions of people each year, particularly in tropical and subtropical regions. Transmitted by Aedes mosquitoes, it can progress to severe forms, especially during secondary infections with a different viral serotype. This is partly due to a mechanism known as Antibody-Dependent...
Dengue is a major arboviral disease affecting millions of people each year, particularly in tropical and subtropical regions. Transmitted by Aedes mosquitoes, it can progress to severe forms, especially during secondary infections with a different viral serotype. This is partly due to a mechanism known as Antibody-Dependent...
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#CHIKV #Vaccine #Epidemiology #GlobalHealth #TropicalDiseases
A vaccine in the shadow of a forgotten virus
With the recent approval of the IXCHIQ (Valneva) and VIMKUNYA (Bavarian Nordic) vaccines, a new era begins in the fight against the chikungunya virus (CHIKV). Yet, the true extent of its global impact remains poorly understood, complicating decisions arou...
A vaccine in the shadow of a forgotten virus
With the recent approval of the IXCHIQ (Valneva) and VIMKUNYA (Bavarian Nordic) vaccines, a new era begins in the fight against the chikungunya virus (CHIKV). Yet, the true extent of its global impact remains poorly understood, complicating decisions arou...
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#WestNile #Mosquito #Epidemiology #Zoonosis
West Nile Virus (WNV), an arbovirus transmitted by mosquitoes and primarily hosted by birds, represents a major public health concern in the Mediterranean region. This zoonotic disease can cause clinical manifestations ranging from mild symptoms to severe encephalitis, especially in the elderly or immunocompromised individuals.
De...
West Nile Virus (WNV), an arbovirus transmitted by mosquitoes and primarily hosted by birds, represents a major public health concern in the Mediterranean region. This zoonotic disease can cause clinical manifestations ranging from mild symptoms to severe encephalitis, especially in the elderly or immunocompromised individuals.
De...
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#Dengue #ImmuneResponse #Immunity #NKCells
#TCells
Dengue is an arboviral disease endemic in over 100 countries and poses a major public health threat. While most cases are mild, severe forms—severe dengue (SD) or dengue hemorrhagic fever—are marked by vascular hyperpermeability, hypovolemic shock, and a risk of death. Notably, these severe manifestations are often th...
Dengue is an arboviral disease endemic in over 100 countries and poses a major public health threat. While most cases are mild, severe forms—severe dengue (SD) or dengue hemorrhagic fever—are marked by vascular hyperpermeability, hypovolemic shock, and a risk of death. Notably, these severe manifestations are often th...
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#Virus #BTB #SertoliCells #ViralInfertility
Long considered an immune-privileged site, the testes are now recognized as a silent yet favored target of several emerging viruses, including Zika, HIV, Ebola and Marburg viruses, and mumps virus. Recent evidence shows that these viral infections can have significant clinical consequences, ranging from fertility di...
Long considered an immune-privileged site, the testes are now recognized as a silent yet favored target of several emerging viruses, including Zika, HIV, Ebola and Marburg viruses, and mumps virus. Recent evidence shows that these viral infections can have significant clinical consequences, ranging from fertility di...
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#Dengue #Psychiatry #Neuropsychiatry
Dengue, often referred to as “seven-day fever” or “breakbone fever,” is a mosquito-borne arboviral disease. Prevalent in tropical and subtropical regions, it poses a major public health challenge due to its high morbidity and the lack of specific antiviral treatments. While neurological complications such as encephalitis or myelitis...
Dengue, often referred to as “seven-day fever” or “breakbone fever,” is a mosquito-borne arboviral disease. Prevalent in tropical and subtropical regions, it poses a major public health challenge due to its high morbidity and the lack of specific antiviral treatments. While neurological complications such as encephalitis or myelitis...
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#Probiotic #Inflammation #GutMicrobiota
#ChronicDisease #GutHealth
Non-communicable diseases (NCDs) such as type 2 diabetes, multiple sclerosis, cardiovascular disorders, and neurodegenerative diseases are now the leading causes of chronic illness and mortality worldwide. These persistent conditions are often associated with an unfavorable biological background marked...
Non-communicable diseases (NCDs) such as type 2 diabetes, multiple sclerosis, cardiovascular disorders, and neurodegenerative diseases are now the leading causes of chronic illness and mortality worldwide. These persistent conditions are often associated with an unfavorable biological background marked...
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2025-07-04
Unsung conductors of food tolerance
Allergology and Immunology Gastroenterology and Hepatology
#OralTolerance
#pTreg #IntestinalInflammation #LymphoidDCs #FoodAllergy
Immune tolerance to food is a cornerstone of gut health. It notably relies on peripheral regulatory T cells (pTreg), which prevent inappropriate reactions to food proteins. But who educates these cells? A U.S. research team has highlighted the crucial role of a rare subtype of dendritic cells expressing RORγt...
Immune tolerance to food is a cornerstone of gut health. It notably relies on peripheral regulatory T cells (pTreg), which prevent inappropriate reactions to food proteins. But who educates these cells? A U.S. research team has highlighted the crucial role of a rare subtype of dendritic cells expressing RORγt...
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#Microbiota #Depression #Alzheimer
#Neuroinflammation #AntiInflammatoryDiet
Mental disorders such as depression, anxiety, bipolar disorder, or schizophrenia—as well as neurodegenerative diseases like Alzheimer’s or Parkinson’s—are major global public health concerns. Their prevalence continues to grow, treatments remain imperfect, and their origins are multifactorial....
Mental disorders such as depression, anxiety, bipolar disorder, or schizophrenia—as well as neurodegenerative diseases like Alzheimer’s or Parkinson’s—are major global public health concerns. Their prevalence continues to grow, treatments remain imperfect, and their origins are multifactorial....
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#Goji #AMD #Macula #Zeaxanthin #Carotenoids
Age-related macular degeneration (AMD) is the third leading cause of blindness worldwide, particularly among older populations. Macular pigment optical density (MPOD), a non-invasive biomarker, reflects the accumulation of protective xanthophyll pigments such as lutein and zeaxanthin. These pigments play a critical role in filt...
Age-related macular degeneration (AMD) is the third leading cause of blindness worldwide, particularly among older populations. Macular pigment optical density (MPOD), a non-invasive biomarker, reflects the accumulation of protective xanthophyll pigments such as lutein and zeaxanthin. These pigments play a critical role in filt...
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#Anthocyanins #OxidativeStress #Microbiota
#CardiovascularHealth #Bioavailability
Anthocyanins are water-soluble plant pigments from the flavonoid family, responsible for the red, purple, and blue hues in many fruits and vegetables. Beyond their coloring function, they exhibit strong bioactive potential—particularly antioxidant, anti-inflammatory, and microbiota-modul...
Anthocyanins are water-soluble plant pigments from the flavonoid family, responsible for the red, purple, and blue hues in many fruits and vegetables. Beyond their coloring function, they exhibit strong bioactive potential—particularly antioxidant, anti-inflammatory, and microbiota-modul...
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2025-06-30
Metabolism in danger: could your plate make the difference?
Cardiology and Vascular Medicine
#MetabolicSyndrome #MediterraneanDiet #Obesity
#Type2Diabetes #Hypertension
Metabolic syndrome (MetS) is a multifactorial disorder affecting up to 40% of Western populations. It is defined by the coexistence of several abnormalities: abdominal obesity, high blood pressure, insulin resistance, and dyslipidemia. This combination greatly increases the risk of t...
Metabolic syndrome (MetS) is a multifactorial disorder affecting up to 40% of Western populations. It is defined by the coexistence of several abnormalities: abdominal obesity, high blood pressure, insulin resistance, and dyslipidemia. This combination greatly increases the risk of t...
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#AI #Transplantation
#MachineLearning #GraftRejection
Solid organ transplantation is currently the gold standard treatment for end-stage organ failure. However, numerous challenges remain, including organ shortages, complex preoperative assessments, and the risk of chronic rejection. In this context, artificial intelligence (AI)—and more specifically, machine learning (ML)—is dr...
Solid organ transplantation is currently the gold standard treatment for end-stage organ failure. However, numerous challenges remain, including organ shortages, complex preoperative assessments, and the risk of chronic rejection. In this context, artificial intelligence (AI)—and more specifically, machine learning (ML)—is dr...
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#Xenotransplantation #LiverTransplantation #GeneticallyModifiedPigLiver
The global shortage of organs hinders access to life-saving transplants, particularly for end-stage liver diseases. In a major medical breakthrough, a team of researchers from Xijing Hospital (China) performed a heterotopic auxiliary xenogeneic liver transplantation by implanting a genetically modif...
The global shortage of organs hinders access to life-saving transplants, particularly for end-stage liver diseases. In a major medical breakthrough, a team of researchers from Xijing Hospital (China) performed a heterotopic auxiliary xenogeneic liver transplantation by implanting a genetically modif...
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